Team Leader
Guus Smit

Molecular Mechanisms of Synaptic Plasticity

I aim to mechanistically understand how assemblies of synaptic proteins contribute to synaptic plasticity in health and disease

Team Leader
Sabine Spijker

Animal Models of Psychiatric Disease

The focus of my team is on cognition and how it is affected by neuropsychiatric ailments, such as depression, addiction, and impulsivity. We study maladaptation of synapses and circuitry brought about by unique molecular signatures in hippocampus and prefrontal cortex.

Team Leader
Ronald van Kesteren

Brain Plasticity in Health and Disease

My research focusses on molecular, cellular and network mechanisms of neuronal and synaptic plasticity in normal brain function and in situations of impaired or altered plasticity, such as healthy aging, Alzheimer’s disease, schizophrenia and neuronal injury.

Team Leader
Mark Verheijen

Glial Regulated Neuronal Plasticity

Our research aims to discover new glial-based mechanisms of information processing in the brain in health and disease, with a focus on the role of astrocytes in the regulation of myelin and synaptic plasticity.

Team Leader
Michel van den Oever

Memory Circuits

The objective of my team is to gain detailed insight in the neural circuitry that mediates the formation and retrieval of stable, long-lasting episodic memories

Team Leader
Ka Wan Li

Neuroproteomics

My Neuroproteomics team aims to (1) describe the protein complex nano-machinery that underlies synapse function and plasticity, and (2) reveal the alteration of synapse/tissue proteomes in cases of neuro-degenerative and neuropsychiatric disorders. Mass spectrometry based quantitative proteomics analysis is the leading technology behind these studies.

Team Leader
Pim van Nierop

Applied Bioinformatics

Modern high-throughput genetics, genomics, and proteomics approaches as performed at CNCR are associated with the production of vast amounts of experimental data. I aim to assist in data and bioinformatics analysis.

Team Leader
Taco de Vries

Addiction

My aim is to unravel the neurobiological mechanisms underlying drug addiction with a particular focus on relapse mechanisms related to alcohol and nicotine. These studies have a strong multidisciplinary character and include behavioural analysis, proteomics, neurophysiology and opto- and chemogenetic approaches.

Team Leader
Joost Verhaagen

Axon Regeneration

The overall objective of the Laboratory for Neuroregeneration is to unravel the biological mechanisms that govern successful regeneration in the PNS and that underlie degeneration and regenerative failure in the CNS. The primary long-term research objective is to make significant contributions to the field of restorative neuroscience and neurology.