Publications

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Highlights 2015-2017

• van Deijk AF, Camargo N, Timmerman J, Heistek T, Brouwers JF, Mogavero F, Mansvelder HD, Smit AB, Verheijen MH. Astrocyte lipid metabolism is critical for synapse development and function in vivo. Glia 2017 Apr;65(4):670-682. doi: 10.1002/glia.23120. Epub 2017 Feb 7.
PMID: 28168742

• Klaassen RV, Stroeder J, Coussen F, Hafner AS, Petersen JD, Renancio C, Schmitz LJ, Normand E, Lodder JC, Rotaru DC, Rao-Ruiz P, Spijker S, Mansvelder HD, Choquet D, Smit AB. Shisa6 traps AMPA receptors at postsynaptic sites and
prevents their desensitization during synaptic activity. Nat Commun. 2016 Mar 2;7:10682.
PubMed PMID: 26931375

• Hondius DC, van Nierop P, Li KW, Hoozemans JJ, van der Schors RC, van Haastert ES, van der Vies SM, Rozemuller AJ, Smit AB. Profiling the human hippocampal proteome at all pathologic stages of Alzheimer’s disease. Alzheimers Dement. 2016 Jun;12(6):654-68.
PubMed PMID: 26772638.

• Lubbers BR, Matos MR, Horn A, Visser E, Van der Loo RC, Gouwenberg Y, Meerhoff GF, Frischknecht R, Seidenbecher CI, Smit AB, Spijker S, van den Oever MC. The Extracellular Matrix Protein Brevican Limits Time-Dependent Enhancement of Cocaine Conditioned Place Preference. Neuropsychopharmacology 2016 Jun;41(7):1907-16.
PubMed PMID: 26711251

• Schmitz SK, King C, Kortleven C, Huson V, Kroon T, Kevenaar JT, Schut D, Saarloos I, Hoetjes JP, de Wit H, Stiedl O, Spijker S, Li KW, Mansvelder HD, Smit AB, Cornelisse LN, Verhage M, Toonen RF. Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1. EMBO J. 2016 Jun 1;35(11):1236-50.
PubMed PMID:27056679

• Schreiber J, Végh MJ, Dawitz J, Kroon T, Loos M, Labonté D, Li KW, Van Nierop P, Van Diepen MT, De Zeeuw CI, Kneussel M, Meredith RM, Smit AB, Van Kesteren RE. Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. J Cell Biol. 2015 Nov 9;211(3):569-86.
PubMed PMID: 26527743

• Fernández E, Li KW, Rajan N, De Rubeis S, Fiers M, Smit AB, Achsel T, Bagni C. FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression. J Neurosci. 2015 Jun 24;35(25):9402-8.
PubMed PMID: 26109663

• Ferreira JS, Schmidt J, Rio P, Águas R, Rooyakkers A, Li KW, Smit AB, Craig AM, Carvalho AL. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015 Jun 3;35(22):8462-79.
PubMed PMID: 26041915

• Wiemhoefer A, Stargardt A, van der Linden WA, Renner MC, van Kesteren RE, Stap J, Raspe MA, Tomkinson B, Kessels HW, Ovaa H, Overkleeft HS, Florea B, Reits EA. Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. Mol Cell Proteomics 2015 Aug;14(8):2177-93.
PubMed PMID: 26041847

• Chavarria-Siles I, White T, de Leeuw C, Goudriaan A, Lips E, Ehrlich S, Turner JA, Calhoun VD, Gollub RL, Magnotta VA, Ho BC, Smit AB, Verheijen MH, Posthuma D. Myelination-related genes are associated with decreased white matter integrity in schizophrenia. Eur J Hum Genet. 2016 Mar;24(3):381-6. PubMed PMID: 26014434

• Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Mol Psychiatry 2015 Nov;20(11):1311-21.
PubMed PMID: 25917366

• de Leeuw C, Goudriaan A, Smit AB, Yu D, Mathews CA, Scharf JM; Tourette Syndrome Association International Consortium for Genetics., Verheijen MH, Posthuma D. Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis. Eur J Hum Genet. 2015 Nov;23(11):1519-22.
PubMed PMID: 25735483

• Dilekoz E, Houben T, Eikermann-Haerter K, Balkaya M, Lenselink AM, Whalen MJ, Spijker S, Ferrari MD, van den Maagdenberg AM, Ayata C. Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. J Neurosci. 2015 Feb 25;35(8):3397-402.
PubMed PMID: 25716839