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Research

We investigate the molecular and cellular mechanisms that underlie the formation and plasticity of synapses and circuitry in animal models of brain disease as well as the human brain.

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Outreach and students@work@MCN

We contribute with our science to the understanding of brain function and disease through publications, at conferences, and by reaching the general public…
Students at MCN contribute to our science…

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About us

The MCN department was initiated in 2003 and in its current form has 35 lab members. MCN is partner in the COsyn consortium, the SUN project, and SynGO. MCN is coordinator of the European innovative doctoral program CognitionNet, and is partner in the EU International training network In-Sens.

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Our latest activities

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Astrocyte-synapse proximity determines memory strength

Aina Badia-Soteras, together with others of the Neuron-Glia Interaction team and collaborators, has shown that retraction of fine astrocyte processes from the synapse is a regulated process that gates the strength of fear memories. This work is published in Biological Psychiatry
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Prevention of microgliosis halts early memory loss in AD

Mandy Kater, together with collaborators of the Memorable consortium, has shown that prevention of microgliosis halts early memory loss in a mouse model of Alzheimer’s disease. This work is published in Brain Behavior and Immunity
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Three CNCR researchers each awarded a VIDI grant

Rik van der Kant, Natalia Goriounova and Priyanka Rao-Ruiz, researchers at the Center for Neurogenomics & Cognitive Research at the Vrije Universiteit Amsterdam, have been awarded by the Dutch Research Council (NWO) with a Vidi grant worth 800,000 euros.